ICSI can be successfully used in patients with fertilization failure after conventional IVF. Failure can also occur due to low sperm count.
What is IVF?
Who need IVF? :
There are several indications for IVF. I t can be discussed under two heading mentioned below:
Male Indication for IVF
Who need IVF ICSI ?
Previous Poor Fertilization with IVF,
What is ICSI?
(Intra Cytoplasmic Sperm Insemination) Highly advanced skilful technique in which with the help of an Inverted microscope injecting a sperm by injecting pipette in to the ova under vision by an Experienced Embryologist.
What is surrogacy?
The current & more accurate term for surrogate is “carrier”. A surrogate is a woman who agrees to carry a pregnancy for another person or couple, called the intended parent(s).
What kind of woman become surrogates?
The typical surrogate is a woman in her mid 20’s to early 35’s married & the mother of her own children. Although compensated, surrogates generally provide their services to help other loving, committed couples experience the same joy they have as parents.
What will be the situation to become a surrogate?
To become a surrogate the woman should fulfill the following criteria:
What is the difference between gestational surrogacy & traditional surrogacy?
In gestational surrogacy, the surrogate is not biologically related to any resulting children. This type of surrogacy requires the use of a third party egg donor (either anonymous or known), and the procedure to establish the pregnancy is called”In Vitro Fertilization”. In traditional surrogacy, the surrogates own eggs are used to conceive the child, so she is biologically related to the resulting children.The procedure used to establish the pregnancy is generally referred to as “ artificial insemination”.
How can we evaluate an IVF center to be scientifically best?
How modern instrumentation is leading to give birth to babies in minimum attempts?
It has been observed worldwide that center should have following instruments to decrease the attempts:
Is male infertility equally important to focus upon compared to female infertility problems?
Can a IVF institute give 100% guarantee programme?
Is the egg retrieval process painful?
Is there a higher risk of birth defects with a child born from IVF?
Does the ovarian stimulation affect the store of eggs resulting early menopause?
Does IVF significantly increase the chances of twins or triplets?
Is it sensible idea to freeze embryo for use at later stage?
How can we be sure that the embryo transferred to the womb are really our own?
Facts of IVF
Do and Don’ts in IVF
What is the relation between Age & IVF?
To avoid recurrent failure, ask following few questions to your IVF doctor
What are their views on egg quality with supported documents?
Q: Will the IVF technique damage my ovaries?
A: There is no evidence to suggest that either normal laparoscopy or ultrasound egg retrieval damages the ovaries. In fact, some reports in the medical literature suggest that following ovarian biopsy, pregnancies occur in couples with a long-term history of infertility.
Q: Will scar tissue around my ovaries make it impossible to retrieve the eggs?
A: Not ordinarily. The surgeon must be able to see the follicles in order to guide the needle to the proper spot for retrieval of the eggs whether by sonographic (ultrasound) or surgical methods.
Q: If an egg is not retrieved or if the technique does not produce a pregnancy on the first attempt, how soon can the procedure be repeated?
A: This depends on the individual. The primary reason for delay is to allow the patient's normal menstrual cycle to resume, which may take 2 to 3 cycles.
Q: How many times will IVF be repeated per couple?
A: There is no specific number. This is determined by the couple together with the physician.
Q: How soon will I know if I'm pregnant?
A: Pregnancy can be confirmed using blood tests about 13 days after egg aspiration. Pregnancy can be confirmed by ultrasound 30 to 40 days after aspiration.
Q: What drugs are given to stimulate the ovarian follicles and to maintain the lining of the uterus prior to implantation of the pre-embryo?
A: Four to five medications normally are given:
1. Leuprolide acetate (Lupron), an injectable drug that blocks secretions of the pituitary gland, thereby optimizing the number of oocytes retrieved;
2. Human menopausal gonadotropin (Pergonal or hMG) or Follicle Stimulating Hormone (Metrodin or FSH), hormones that stimulate ovarian activity, are injected daily for about 6-10 days prior to the procedure;
3. Human chorionic gonadotropin (hCG), a hormone that mimics the action of the hormone which naturally induces ovulation, is injected 34 to 36 hours before retrieval and may be used after retrieval to supplement natural progesterone production;
4. Progesterone, a natural hormone that enables the uterus to support pregnancy, may be used as a daily injection after egg retrieval; and micronized vaginal persance & vaginal gel will be a drug of choice.
Q: What side effects, if any, can these drugs cause?
A: No pronounced side effects have been associated with any of these drugs. However, the patient should inform the physician of ANY allergies she has or of any previous adverse reactions to drugs.
Q: Will I have an egg in every follicle?
A: It varies from patient to patient . As many as half of the follicles may not contain an egg in some patients.
Q: How much time does the entire procedure require?
A: Approximately three weeks (all as an outpatient). Fertility drugs are administered to stimulate the ovaries. Then during the four to six days prior to ovulation, the patient is monitored by ultrasound as well as by hormone levels.
Q: What happens to any extra pre-embryos?
A: A maximum of four pre-embryos will be transferred to the uterus for possible implantation. Patients will have several other options regarding the disposition of the remaining pre-embryos. One option is to freeze pre-embryos for your later use. Other options are to donate or simply dispose of them. Excess pre-embryos, if any, belong to you, and you will determine what is to be done.
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