Recurrent IVF Failure
Failure to achieve a pregnancy after 3 completed fresh IVF-ET cycles
Patient Selection criteria at Wings: Factors implicated
RIF Treatment strategy at Wings Hospital includes two steps:
We measure the size of the endometrium by 4D sonography. In case endometrium is less than 7 mm and volume is less than 3 cc, we always explain regarding the poor output of implantation. Any case of 7-8 mm endometrium or more than 8 mm endometrium with any ecogenecity in sonography and previous 3 failures, the only requirement in Hysteroscopy.
At Wings, any visible Hydrosalpinges are removed by Laparoscopy.
Ovarian Stimulation at Wings:
Controlled ovarian stimulation will always lead to optimal collection of the eggs leading to decreased failure rates.
In house Embryologist team leads to better selection of the gamets. In house embryologist can give more time for all the embryological activities which directly impact the success rates. For transfer of 5th day blastocyst, it is always essential to have full time in-house Embryologist.
Stringent protocol for prevention of infection is extremely important and maintaining body temperature wherever handling of the gamets is required at 37 degree C.
Working Methodology at Wings Hospital:
Tailoring for embryo in each cases:
Better Gamet selection in Male infertility
In case of Azoospermia, we are the only institute offering Micro-TESA and Micro-PESA for better aspiration of the sperm from the testis and epididymis
Infrastructure to tackle RIF @ Wings
High end culturing incubators for better growth of the embryos. Separate Triple gas incubators, time lapse technique incubators. It will increase the selection criteria of morphologically sound embryo leading to 15% less abortion rates and more implantations.
What is PGD,PGS, ERA?
Preimplantation genetic diagnosis (PGD) for single gene disorders is a powerful genetic test that may be performed during IVF treatment to screen embryos that are at risk to develop a serious genetic disease. PGD is performed on a small embryo biopsy and identifies which embryos are not at increased risk of developing the disease. The goal of PGD testing is to help couples build a healthy family. PGD is done before the pregnancy is established and helps avoid difficult decisions and situations.
Preimplantation genetic screening (PGS) for aneuploidy is a powerful genetic test that may be performed on embryos during IVF treatment to screen for numerical chromosomal abnormalities. PGS is performed on a small embryo biopsy prior to transfer and identifies which embryos are chromosomally normal. Chromosomally normal embryos are the most likely to develop to term and to be born as a healthy baby. PGS testing helps IVF physicians and patients decide which embryos to transfer.
ERA indicates the window of implantation(WOI), increasing your chances of successful transfer
At Wings, we offer the above services in a combined manner in case of recurrent implantation failure.